2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) affects the thyroid morphologically and/or functionally in adult animals. Recently, the National Toxicology Program conducted a 2-year gavage study of TCDD in female Harlan Sprague–Dawley rats. The only treatment-related alterations found in thyroid follicles were decreased luminal size and increased height of the follicular epithelial cells, without prominent protrusion into the lumen.
Cells, Free Full-Text
A review of species differences in the control of, and response to
Low dose exposure to HBCD, CB-153 or TCDD induces
A) Follicular hypertrophy in the thyroid in a female rat exposed to a
Thyroid gland. Hyperplasia of the follicle-lining epithelial cells.
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A review of species differences in the control of, and response to
Proceedings of the 2009 National Toxicology Program Satellite
Follicular hyperplasia - Wikipedia
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Resveratrol has anti-thyroid effects both in vitro and in vivo
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Recommendations from the INHAND Apoptosis/Necrosis Working Group
