Background We encountered a woman with vaginal cancer that was associated with complete uterine prolapse and complicated by severe intrauterine adhesions. In this case report, we describe the clinical course and successful treatment of this rare condition. Case presentation A 78-year-old woman (gravida 10, para 2, abortion 8) with a 10-year history of uterine prolapse presented for evaluation of bleeding from an ulceration on the surface of the irreducibly prolapsed uterus. Biopsy of a mass on her vaginal wall led to a diagnosis of keratinizing squamous cell carcinoma. Her history of eight abortion procedures had resulted in severe intrauterine adhesions, preventing tandem insertion and intracavitary brachytherapy. She was also ineligible for surgery under general anesthesia + chemotherapy because of her advanced age and presence of arrhythmia. Therefore, we devised an extensive treatment plan involving high-dose-rate interstitial brachytherapy. This treatment successfully eliminated the squamous cell carcinoma as confirmed by biopsy with no recurrence or severe late complications. Conclusions We found that high-dose-rate interstitial brachytherapy may be a very effective therapeutic strategy for this condition with few adverse effects.
Vaginal Cancer: Causes, Symptoms, Types, Risk Factors, Diagnosis, Treatment, Prevention and Complications
Uterine Cancer - HealthyWomen
Cancer Treatment and Pelvic Health - A Womans Health
Process of paper selection. Abbreviation: VAIN, vaginal intraepithelial
Radiation therapy for vaginal cancer in complete uterine prolapse with intrauterine adhesion: a case report, BMC Women's Health
PDF) Using a pessary during radiotherapy in reducible pelvic organ prolapse and vaginal cancer: a case report and review of the literature
Vaginal cancer Information
Chemoradiotherapy in a patient with locally advanced small cell neuroendocrine carcinoma of the cervix complicated by pelvic organ prolapse: A case report - ScienceDirect
Kaplan-Meier curves demonstrating (A) improved local control (p =
Uterine Prolapse Complicated by Vaginal Cancer: A Case Report and Literature Review
Treatment patterns and survival outcomes in patients with cervical cancer complicated by complete uterine prolapse: a systematic review of literature
Frequently Asked Questions and Answers about Brachytherapy - Neolife Tıp Merkezi
Axial computed tomography scan demonstrating four interstitially
Treatment characteristics of early stage vaginal cancer patients (n = 10).
Vaginectomy - Wikipedia
